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Acetyl-CoA Carboxylase beta 抗体 (pSer220) (Cy5)

This Cy5-conjugated 兔 多克隆 anti-Acetyl-CoA Carboxylase beta antibody specifically detects Acetyl-CoA Carboxylase beta in IF (cc) 和 IF (p). The antibody is reactive with 人 samples.
产品编号 ABIN1703717
发货至: 中国
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Quick Overview for Acetyl-CoA Carboxylase beta 抗体 (pSer220) (Cy5) (ABIN1703717)

抗原

See all Acetyl-CoA Carboxylase beta (ACACB) 抗体
Acetyl-CoA Carboxylase beta (ACACB)

适用

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宿主

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克隆类型

  • 22
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多克隆

标记

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This Acetyl-CoA Carboxylase beta antibody is conjugated to Cy5

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    pSer220

    预测反应

    Human

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human Acetyl Coenzyme A Carboxylase beta around the phosphorylation site of Ser220

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Acetyl-CoA Carboxylase beta (ACACB)

    别名

    Acetyl Coenzyme A Carboxylase beta

    背景

    Synonyms: Acetyl Coenzyme A Carboxylase beta phospho S220, Acetyl Coenzyme A Carboxylase beta phospho Ser2210 p-Acetyl Coenzyme A Carboxylase beta phospho S220, ACACB_HUMAN

    Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

    UniProt

    O00763

    途径

    AMPK Signaling, Ribonucleoside Biosynthetic Process
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