TRIM22 抗体 (AA 231-330) (Cy5)
Quick Overview for TRIM22 抗体 (AA 231-330) (Cy5) (ABIN1703706)
抗原
See all TRIM22 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 231-330
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Trim22
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- TRIM22 (Tripartite Motif Containing 22 (TRIM22))
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别名
- Trim22/Staf-50
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背景
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Synonyms: 50 kDa stimulated trans acting factor, RING finger protein 94, RNF94, Staf 50, STAF50, Stimulated trans acting factor 50 kDa, Stimulated Trans Acting Factor homolog of Mouse Rpt 1 gene, Trim22, Tripartite binding mot 22, Tripartite mot containing protein 22, TTRIM22RIM22, TRI22_HUMAN.
Background: The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. Staf-50 (50 kDa-stimulated trans-acting factor), also known as TRIM22 (tripartite motif-containing 22), RNF94 or GPSTAF50, is a 498 amino acid cytoplasmic protein that belongs to the TRIM family and, characteristic of TRIM family members, contains one RING-type zinc finger, one B box-type zinc finger and one SPRY domain. Induced by IFN-å, and IFN-, Staf-50 is strongly expressed in ovary, spleen, thymus and peripheral blood leukocytes where it is thought to mediate the antiviral effects of IFN proteins. Additionally, Staf-50 is present in leukemic cells, suggesting a role in cancer formation and metastasis. Staf-50 exists as two alternatively spliced isoforms which are encoded by a gene that maps to human chromosome 11.
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基因ID
- 10346
抗原
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