Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA) (AA 51-150) 抗体 (Cy5)
Quick Overview for Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA) (AA 51-150) 抗体 (Cy5) (ABIN1703616)
抗原
See all Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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预测反应
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FARSLA/CML33
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
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别名
- FARSLA/CML33
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背景
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Synonyms: CML 33, CML33, FARS, FARSA, FARSL, FRSA, PheHA, Phenylalanine tRNA ligase 1 alpha cytoplasmic, Phenylalanine tRNA ligase alpha chain, Phenylalanine tRNA synthetase alpha subunit, Phenylalanine tRNA synthetase like alpha subunit, Phenylalanyl tRNA synthetase alpha chain, Phenylalanyl tRNA synthetase alpha subunit, Phenylalanyl tRNA synthetase like alpha subunit, PheRS.
Background: Aminoacyl-tRNA synthetases consist of a family of enzymes that catalyze the specific aminoacylation of tRNA by their cognate amino acid in the initial step of ribosome-dependent protein biosynthesis. FARSLA, also known as FRSA, CML33, FARSL or PheHA (phenylalanyl-tRNA synthetase, alpha subunit), is a member of the class-II aminoacyl-tRNA synthetase family and is highly expressed in proliferating cells of bone marrow. FARSLA is a cytoplasmic phenylalanine-tRNA synthetase that functions as a heterodimer consisting of a catalytic alpha-subunit and a regulatory beta-subunit. The alpha-subunit is responsible for forming the amino acid binding pocket, mediating the ATP/aminoacyl adenylate binding, and interacts with the acceptor stem of the tRNA. FARSLA functions in a cell cycle-dependent and differentiation-dependent manner.
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基因ID
- 10160
抗原
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