FNBP1 抗体 (AA 331-430) (Cy3)
Quick Overview for FNBP1 抗体 (AA 331-430) (Cy3) (ABIN1702844)
抗原
See all FNBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 331-430
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交叉反应
- Pufferfish, 非洲爪蟾
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Zebrafish
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FBP17
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亚型
- IgG
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anti-Formin Binding Protein 1 (FNBP1) (Internal Region) antibody
Verified FNBP1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Formin Binding Protein 1 (FNBP1) (N-Term) antibodyFNBP1 适用: 人, 大鼠, 小鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Formin Binding Protein 1 (FNBP1) (AA 348-529) antibodyFNBP1 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- FNBP1 (Formin Binding Protein 1 (FNBP1))
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别名
- FBP17
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背景
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Synonyms: FBP1, FBP17, FNBP1, FNBP1_HUMAN, Formin binding protein 1, Formin binding protein 17, Formin-binding protein 1, Formin-binding protein 17, hFBP17, KIAA0554, MGC126804.
Background: FNBP1 is a 617 amino acid protein that localizes to a variety of locations within the cell, including the cytoplasm, cytoskeleton, lysosome and the cell cortex, and contains one FCH domain, one REM repeat and one SH3 domain. Expressed at high levels in respiratory, reproductive and urinary systems, as well as in brown adipose tissue and epithelial cells of the gastrointestinal tract, FNBP1 interacts with Rho 7 and links the Actin cytoskeleton with Rho 7 signaling, playing a crucial role in membrane tubulation and cytoskeletal reorganization during endocytosis. Additionally, FNBP1, which exists as four alternatively spliced isoforms, enhances Actin polymerization and promotes membrane invagination and the formation of tubules. Chromosomal aberrations in the FNBP1 gene are associated with acute leukemias, suggesting a role for defective FNBP1 in carcinogenesis.
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基因ID
- 23048
抗原
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