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FIP1L1 抗体 (AA 501-594) (Cy3)

This anti-FIP1L1 antibody is a 兔 多克隆 antibody detecting FIP1L1 in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1702471
发货至: 中国

Quick Overview for FIP1L1 抗体 (AA 501-594) (Cy3) (ABIN1702471)

抗原

See all FIP1L1 抗体
FIP1L1 (FIP1 Like 1 (FIP1L1))

适用

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宿主

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克隆类型

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多克隆

标记

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This FIP1L1 antibody is conjugated to Cy3

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 501-594

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human FIP1L1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    FIP1L1 (FIP1 Like 1 (FIP1L1))

    别名

    FIP1L1

    背景

    Synonyms: DKFZp586K0717, Factor interacting with PAP, FIP1, FIP1 like 1 S cerevisiae, FIP1 like 1, FLJ33619, hFip 1, hFip1, Pre mRNA 3 end processing factor FIP1, Rearranged in hypereosinophilia, RHE, FIP1_HUMAN.

    Background: The Component of the Cleavage and Polyadenylation Specificity Factor (CPSF) complex plays an important role in the 3'-end formation of pre-mRNA. This complex recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase to process and add to the poly(A) tail. FIP1L1 (FIP1-like 1), also known as Pre-mRNA 3'-end-processing factor FIP1, FIP1 (Factor interacting with PAP) and RHE (Rearranged in hypereosinophilia), is a 594 amino acid nuclear protein that is a component of the CPSF complex. Within the complex, FIP1L1 contributes to the poly(A) recognition and stimulates poly(A) addition. Fusion of the genes encoding FIP1L1 and PDGFRA due to an interstitial deletion on chromosome 4q12 is the cause of hypereosinophilia syndrome, a rare blood disorder characterized by continuous overproduction of eosinophils in the bone marrow that leads to tissue infiltration and organ damage. There are three isoforms of FIP1L1 that are produced as a result of alternative splicing events.

    基因ID

    81608
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