CSGALNACT1 抗体 (AA 101-200) (Cy3)
Quick Overview for CSGALNACT1 抗体 (AA 101-200) (Cy3) (ABIN1702446)
抗原
See all CSGALNACT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-200
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CSGALNACT1
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CSGALNACT1 (Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1 (CSGALNACT1))
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别名
- CSGALNACT1
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背景
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Synonyms: 4-N-acetylgalactosaminyltransferase 1, Beta4GalNAcT 1, beta4GalNAcT, Beta4GalNAcT-1, Beta4GalNAcT1, CGAT1_HUMAN, ChGn, Chondroitin beta-1, Chondroitin beta1 4 N acetylgalactosaminyltransferase, Chondroitin beta1 4 N acetylgalactosaminyltransferase 1, Chondroitin sulfate N acetylgalactosaminyltransferase 1, Chondroitin sulfate N-acetylgalactosaminyltransferase 1, CSGalNAcT 1, CsGalNAcT-1, Csgalnact1, FLJ11264, FLJ13760.
Background: The chondroitin N-acetylgalactosaminyltransferase family includes Beta-1,4-GalNAc-T, Beta-1,4-GalNAc-T2, Beta-1,4-GalNAc-T3 and Beta-1,4-GalNAc-T4. The Beta-1,4-GalNAc-T protein consists of a short N-terminal residue, a transmembrane region and a long C-terminal residue, which includes a catalytic domain and localizes to the Golgi apparatus. Beta-1,4-GalNAc-T utilizes simple ganglioside GM3 as a substrate for more complex gangliosides GM2, GM1 and GD1a. Beta-1,4-GalNAc-T is expressed in normal brain tissues and in various malignant transformed cells, such as malignant melanoma, neuroblastoma and adult T cell leukemia. Mice lacking the Beta-1,4-GalNAc-T protein develop significant and progressive behavioral neuropathies, including deficits in reflexes, strength, coordination and balance. Beta-1,4-GalNAc-T is a potential molecular marker for detecting melanoma cells and monitoring tumor progression.
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基因ID
- 55790
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途径
- Glycosaminoglycan Metabolic Process
抗原
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