BTBD14A 抗体 (AA 401-500) (Cy3)
Quick Overview for BTBD14A 抗体 (AA 401-500) (Cy3) (ABIN1702352)
抗原
See all BTBD14A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 401-500
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human BTBD14A
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))
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别名
- BTBD14A
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背景
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Synonyms: BTB POZ domain containing 14A, BTB domain containing 14A, BTB/POZ domain containing protein 14A, BTB/POZ domain-containing protein 14A, BTBD 14A, BTBD14, NAC-2, NACC2, NACC2_HUMAN, Nucleus accumbens-associated protein 2.
Background: BTBD14A is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.
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基因ID
- 54813
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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