GRB14 抗体 (AA 221-320) (Cy3)
Quick Overview for GRB14 抗体 (AA 221-320) (Cy3) (ABIN1702143)
抗原
See all GRB14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 221-320
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特异性
- This antibody may also detect the similar protein GRB10 due to an 83 % sequence similarity in the immunogen sequence.
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交叉反应
- 人
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预测反应
- Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GRB 14
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亚型
- IgG
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anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (AA 294-397) antibody
GRB14 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (AA 14-48) antibodyGRB14 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB57897 unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (Internal Region) antibodyGRB14 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (AA 221-320) antibodyGRB14 适用: 人 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) antibodyGRB14 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (Internal Region) antibodyGRB14 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (AA 251-300) antibodyGRB14 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
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别名
- GRB 14
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背景
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Synonyms: Growth factor receptor-bound protein 14, GRB14 adapter protein, GRB14
Background: Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
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基因ID
- 2888
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UniProt
- Q14449
抗原
-
