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STAP2 抗体 (AA 151-250) (Cy3)

This anti-STAP2 antibody is a 兔 多克隆 antibody detecting STAP2 in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1701887
发货至: 中国

Quick Overview for STAP2 抗体 (AA 151-250) (Cy3) (ABIN1701887)

抗原

See all STAP2 抗体
STAP2 (Signal Transducing Adaptor Family Member 2 (STAP2))

适用

  • 34
  • 2
  • 1

宿主

  • 31
  • 3
  • 1

克隆类型

  • 34
  • 1
多克隆

标记

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  • 1
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This STAP2 antibody is conjugated to Cy3

应用范围

  • 35
  • 16
  • 12
  • 12
  • 11
  • 6
  • 3
  • 3
  • 2
  • 1
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 7
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    • 2
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    • 1
    • 1
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    AA 151-250

    预测反应

    Human

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human STAP2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    STAP2 (Signal Transducing Adaptor Family Member 2 (STAP2))

    别名

    STAP2

    背景

    Synonyms: BKS, Breast tumor kinase substrate, BRK substrate, Signal transducing adaptor protein 2, Signal-transducing adaptor protein 2, Ssignal transducing adaptor family member 2, STAP 2, STAP-2, STAP2, STAP2_HUMAN.

    Background: Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues (1,2). Kinases are capable of influencing the oncogenic potential of cell sytems at the level of oncoprotein or tumor suppressor protein phosphorylation states (1,2). STAP-2 is a protein that contains a pleckstrin homology (PH) domain and an SH2 domain, and associates with BRK (3). BRK (breast tumor kinase, Sik) is a 451 amino acid, nonreceptor protein-tyrosine kinase that is overexpressed in breast tumors and metastatic melanoma cell lines (4). Similar to the Src family of intracellular kinses, BRK is comprised of an SH3 domain, an SH2 domain, and a catalytic domain (5). STAP-2 is susceptiple to tyrosine phosphorylation and may be invovled in tyrosine kinase-mediated signaling cascades, whose aberrant function may lead to metastis (3).

    基因ID

    55620

    UniProt

    Q9UGK3
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