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FOXH1 抗体 (AA 41-140) (Biotin)

This Biotin-conjugated 兔 多克隆 anti-FOXH1 antibody specifically detects FOXH1 in WB, ELISA, IHC (p) 和 IHC (fro). The antibody is reactive with 小鼠 samples.
产品编号 ABIN1701505
发货至: 中国
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Quick Overview for FOXH1 抗体 (AA 41-140) (Biotin) (ABIN1701505)

抗原

See all FOXH1 抗体
FOXH1 (Forkhead Box H1 (FOXH1))

适用

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小鼠

宿主

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克隆类型

  • 46
多克隆

标记

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This FOXH1 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 41-140

    交叉反应

    小鼠

    预测反应

    Human,Rat,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human FOXH1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    FOXH1 (Forkhead Box H1 (FOXH1))

    别名

    FOXH1

    背景

    Synonyms: FAST 1, Fast 2, Fast-1, Fast-2, FAST1, Fast2, Forkhead activin signal transducer 1, Forkhead activin signal transducer 2, Forkhead box H1, Forkhead box protein H1, FOX H1, FOXH 1, FOXH1, FOXH1_HUMAN, hFAST 1, hFAST-1, hFAST1, Human homolog of Xenopus forkhead activin signal transducer 1, TGF beta/Activin signal transducer FAST1.

    Background: Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGß, and activin, indicating that these FAST proteins mediate TFGß, induced signal transduction (3).

    基因ID

    8928

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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