Complement Component C9b (C9b) (AA 251-350) 抗体 (Biotin)
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北京 101111
Quick Overview for Complement Component C9b (C9b) (AA 251-350) 抗体 (Biotin) (ABIN1701212)
抗原
See all Complement Component C9b (C9b) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 251-350
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Dog,Cow,Sheep,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Complement component C9b
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亚型
- IgG
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anti-Complement Component C9b (C9b) (AA 251-350) antibody
C9b 适用: 人, 小鼠 WB, FACS, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- Complement Component C9b (C9b)
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别名
- Complement component C9b
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背景
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Synonyms: CO9_HUMAN, Complement component C9, Complementcomponent C9b.
Background: C9 is a plasma protein synthesized in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerization of 12-18 C9 Molecules. These polymerized C9 Molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.
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基因ID
- 735
抗原
-
