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EXTL3 抗体 (AA 351-450) (Biotin)

This anti-EXTL3 antibody is a 兔 多克隆 antibody detecting EXTL3 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 大鼠.
产品编号 ABIN1700939
发货至: 中国
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北京 101111
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Quick Overview for EXTL3 抗体 (AA 351-450) (Biotin) (ABIN1700939)

抗原

See all EXTL3 抗体
EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))

适用

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大鼠

宿主

  • 55

克隆类型

  • 54
多克隆

标记

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This EXTL3 antibody is conjugated to Biotin

应用范围

  • 44
  • 26
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 6
    • 5
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    • 2
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    • 1
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    AA 351-450

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human EXTL3

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))

    别名

    EXTL3

    背景

    Synonyms: botv, DKFZp686C2342, Exostoses multiple-like 3, Exostoses-like 3, Exostosin-like 3, EXT-related protein 1, EXTL1L, EXTL3, EXTL3_HUMAN, EXTR1, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferas, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Hereditary multiple exostoses gene isolog, KIAA0519, Multiple exostosis-like protein 3, Putative tumor suppressor protein EXTL3, REG, Reg receptor, REGR, RPR.

    Background: EXTL3 is a member of the EXT (hereditary multiple exostosin) gene family of tumor suppressors encoding glycosyltransferases involved in heparan sulfate (HS) biosynthesis. Within this family, the C-terminus is conserved between all members from C. elegans to vertebrates. EXTL3 is a ubiquitously expressed, developmentally regulated, single-pass type II membrane protein that localizes to the endoplasmic reticulum membrane. EXTL3 adds N-acetylglucosamine (GlcNAc) to the polysaccharide-protein linkage region and to the growing HS chain suggesting that it plays a role in both the initiation and elongation of HS chains. In addition, EXTL3 may act as a Reg receptor, binding Reg via its N-terminus.

    基因ID

    2137

    途径

    Glycosaminoglycan Metabolic Process, ER-Nucleus Signaling
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