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CRTAP 抗体 (AA 201-300) (Biotin)

CRTAP 适用: 人 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1700583
发货至: 中国
  • 抗原 See all CRTAP 抗体
    CRTAP (Cartilage Associated Protein (CRTAP))
    抗原表位
    • 14
    • 9
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    适用
    • 41
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
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    • 2
    • 2
    • 1
    • 1
    宿主
    • 41
    • 1
    克隆类型
    • 41
    • 1
    多克隆
    标记
    • 19
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    This CRTAP antibody is conjugated to Biotin
    应用范围
    • 41
    • 18
    • 13
    • 13
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    预测反应
    Mouse,Rat,Dog,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CRTAP
    亚型
    IgG
    Top Product
    Discover our top product CRTAP Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    CRTAP (Cartilage Associated Protein (CRTAP))
    别名
    CRTAP (CRTAP 产品)
    别名
    zgc:85621 antibody, wu:fb47h01 antibody, CASP antibody, LEPREL3 antibody, OI7 antibody, 5730529N23Rik antibody, Leprel3 antibody, RGD1565180 antibody, cartilage associated protein antibody, cartilage-associated protein antibody, crtap antibody, CRTAP antibody, LOC5574430 antibody, CpipJ_CPIJ013810 antibody, Crtap antibody
    背景

    Synonyms: Cartilage associated protein, LEPREL3, leprecan-like 3, CASP, CRTAP_HUMAN.

    Background: CRTAP is a secreted protein localizing to the extracellular space that plays a role in collagen post-translational modifications, extracellular fibril assembly and intracellular trafficking. CRTAP is widely expressed with predominant expression in articular chondrocytes. It contains a signal peptide and a tetratricopeptide-like helical domain and is essential for normal bone formation. In the endoplasmic reticulum (ER), CRTAP forms a complex with Gros1 and CyPB (cyclophilin B) and is required for the efficient 3-hydroxylation of target prolyl residues in Collagen Type I molecules, the major structural proteins of skin and bone. Mutations in the gene encoding CRTAP can lead to autosomal recessive osteogenesis imperfecta (OI) type 7 and type 2B. OI, also known as brittle bone disease, is characterized by bone fragility and susceptibility to fractures. OI type 7 is a mild form of this disorder, while OI type 2B is a neonatal lethal condition.

    基因ID
    10491
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