C8ORF58 抗体 (AA 251-365) (Biotin)
Quick Overview for C8ORF58 抗体 (AA 251-365) (Biotin) (ABIN1700229)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 251-365
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交叉反应
- 人, 大鼠
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预测反应
- Mouse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human C8orf58
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亚型
- IgG
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anti-Chromosome 8 Open Reading Frame 58 (C8ORF58) (AA 251-365) antibody
C8ORF58 适用: 人, 大鼠 WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- C8ORF58 (Chromosome 8 Open Reading Frame 58 (C8ORF58))
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别名
- C8orf58
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背景
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Synonyms: C8orf58, CH058_HUMAN, Chromosome 8 open reading frame 58, Uncharacterized protein C8orf58.
Background: C8orf58 (chromosome 8 open reading frame 58) is a 365 amino acid protein that exists as two alternatively spliced isoforms, which are encoded by a gene that maps to human chromosome 8p21. Consisting of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.
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基因ID
- 541565
抗原
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