GALE 抗体 (AA 21-120) (AbBy Fluor® 647)
Quick Overview for GALE 抗体 (AA 21-120) (AbBy Fluor® 647) (ABIN1699633)
抗原
See all GALE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-120
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GALE/Galactowaldenase
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- GALE (UDP-Galactose-4-Epimerase (GALE))
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别名
- GALE/Galactowaldenase
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背景
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Synonyms: FLJ95174, FLJ97302, Galactose 4 epimerase UDP, Galactowaldenase, galE, GALE_HUMAN, OTTHUMP00000002991, OTTHUMP00000002994, OTTHUMP00000037931, OTTHUMP00000044857, SDR1E1, short chain dehydrogenase/reductase family 1E member 1, UDP galactose 4 epimerase, UDP glucose 4 epimerase, UDP-galactose 4-epimerase, UDP-glucose 4-epimerase.
Background: GALE is a 348 amino acid protein that functions as the third enzyme in the Leloir pathway of galactose metabolism. A member of the sugar epimerase family, GALE exists as a homodimer, binds FAD as a cofactor and catalyzes the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine and UDP-glucose to UDP-galactose. The gene encoding GALE maps to human chromosome 1p36.11 and mutations in this gene lead to the development of complex disorder known as epimerase-deficiency galactosemia (EDG) or galactosemia type 3, which is characterized by mental retardation, liver damage, cataracts and deafness.
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基因ID
- 2582
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途径
- Response to Water Deprivation, Cellular Glucan Metabolic Process
抗原
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