PUM2 抗体 (AA 901-1066) (AbBy Fluor® 647)
Quick Overview for PUM2 抗体 (AA 901-1066) (AbBy Fluor® 647) (ABIN1698909)
抗原
See all PUM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 901-1066
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Pumilio 2
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))
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别名
- Pumilio 2
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背景
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Synonyms: FLJ36528, KIAA0235, MGC138251, MGC138253, PUM 2, Pum2, PUM2, PUMH2, Pumilio Drosphila homolog 2, Pumilio homolog 2 Drosophila, Pumilio homolog 2, Pumilio2, PUM2_HUMAN.
Background: Pumilio 2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding mRNA targets. It supports proliferation and self-renewal of stem cells by regulating the translation of key transcripts. The Pumilio gene encodes proteins that are required for development of germ stem cells in one or both sexes. The Pumilio protein interacts with the human Nanos1 protein and this interaction may play a conserved role in germ cell development. Pumilio 2 is highly expressed in testis and ovary and at lower levels in brain, heart, kidney, liver, muscle, placenta, intestine and stomach. It is also expressed in stem cells, germ cells and in most fetal tissues.
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基因ID
- 23369
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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