C9ORF173 抗体 (AbBy Fluor® 555)
Quick Overview for C9ORF173 抗体 (AbBy Fluor® 555) (ABIN1697301)
抗原
适用
宿主
克隆类型
标记
应用范围
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交叉反应
 - 小鼠
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预测反应
 - Human,Rat,Dog
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纯化方法
 - Purified by Protein A.
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免疫原
 - KLH conjugated synthetic peptide derived from human C9orf173
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亚型
 - IgG
 
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应用备注
 - IF(IHC-P) 1:50-200
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 μg/μL
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缓冲液
 - Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
 - 12 months
 
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- C9ORF173 (Chromosome 9 Open Reading Frame 173 (C9ORF173))
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别名
 - C9orf173
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背景
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Synonyms: C9orf173, Chromosome 9 open reading frame 173, CI173_HUMAN, Uncharacterized protein C9orf173.
Background: C9orf173 (chromosome 9 open reading frame 173) is a 389 amino acid protein that exists as four alternatively spliced isoforms. The gene encoding C9orf173 maps to human chromosome 9q34.3. Chromosome 9 consists of about 145 million bases, represents 4 % of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
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基因ID
 - 441476
 
抗原
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