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FN3K 抗体 (AA 201-309) (AbBy Fluor® 555)

This anti-FN3K antibody is a 兔 多克隆 antibody detecting FN3K in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1696661
发货至: 中国

Quick Overview for FN3K 抗体 (AA 201-309) (AbBy Fluor® 555) (ABIN1696661)

抗原

See all FN3K 抗体
FN3K (Fructosamine 3 Kinase (FN3K))

适用

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宿主

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克隆类型

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多克隆

标记

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This FN3K antibody is conjugated to AbBy Fluor® 555

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 201-309

    预测反应

    Human,Mouse,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human FN3K

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    FN3K (Fructosamine 3 Kinase (FN3K))

    别名

    FN3K

    背景

    Synonyms: 2310074G21Rik, Fnsk, Fructosamine 3 kinase, RP23-293H17.4, FN3K_HUMAN.

    Background: Amines, including those present on proteins, spontaneously react with glucose to make fructosamines in a reaction termed glycation. Fructosamine 3-kinase (FN3K), a 309-amino acid enzyme initially identified in erythrocytes, catalyzes the ATP-dependent phosphorylation of the third carbon on both D- and L-fructosamines, leading to their destabilization and eventually, their removal from the protein. FN3K is a monomer that is ubiquitously expressed in mammalian tissue and phosphorylates both low molecular mass and protein-bound fructosamines which are formed as a result of glycation of glucose with primary amines. FN3K protects proteins from the harmful effects of nonenzymatic glycation, and may also be involved in peptide repair and cell metabolism. FN3KRP (fructosamine-3-kinase-related protein) is a 309 amino acid protein that is expressed in erythrocytes, bone marrow, spleen, brain and kidney and belongs to the fructosamine kinase family. FN3KRP functions to phosphorylate psicoamines and ribulosamines on the third carbon of their sugar moiety, thereby leading to the deglycation of the target amines.

    基因ID

    64122
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