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GLUD2 抗体 (AA 21-120) (AbBy Fluor® 488)

This anti-GLUD2 antibody is a 兔 多克隆 antibody detecting GLUD2 in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1695601
发货至: 中国

Quick Overview for GLUD2 抗体 (AA 21-120) (AbBy Fluor® 488) (ABIN1695601)

抗原

See all GLUD2 抗体
GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))

适用

  • 48
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  • 8
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  • 1
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  • 1

宿主

  • 44
  • 4

克隆类型

  • 47
  • 1
多克隆

标记

  • 20
  • 2
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  • 1
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  • 1
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This GLUD2 antibody is conjugated to AbBy Fluor® 488

应用范围

  • 42
  • 15
  • 12
  • 12
  • 7
  • 6
  • 4
  • 3
  • 1
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  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 9
    • 4
    • 4
    • 4
    • 1
    • 1
    AA 21-120

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GLUD2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))

    别名

    GLUD2

    背景

    Synonyms: GDH 2, GDH, GDH2, GLUDP1, Glutamate dehydrogenase 2, Glutamate dehydrogenase 2 mitochondrial, Glutamate dehydrogenase pseudogene 1.

    Background: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.

    基因ID

    2747

    途径

    Synaptic Membrane
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