C9ORF173 抗体 (AbBy Fluor® 488)
Quick Overview for C9ORF173 抗体 (AbBy Fluor® 488) (ABIN1695477)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 小鼠
-
预测反应
- Human,Rat,Dog
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human C9orf173
-
亚型
- IgG
-
-
-
-
应用备注
- IF(IHC-P) 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- C9ORF173 (Chromosome 9 Open Reading Frame 173 (C9ORF173))
-
别名
- C9orf173
-
背景
-
Synonyms: C9orf173, Chromosome 9 open reading frame 173, CI173_HUMAN, Uncharacterized protein C9orf173.
Background: C9orf173 (chromosome 9 open reading frame 173) is a 389 amino acid protein that exists as four alternatively spliced isoforms. The gene encoding C9orf173 maps to human chromosome 9q34.3. Chromosome 9 consists of about 145 million bases, represents 4 % of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
-
基因ID
- 441476
抗原
-
