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FBLN2 抗体 (AA 501-600) (AbBy Fluor® 488)

This AbBy Fluor® 488-conjugated 兔 多克隆 anti-FBLN2 antibody specifically detects FBLN2 in WB, IF (cc) 和 IF (p). The antibody is reactive with 人 samples.
产品编号 ABIN1695415
发货至: 中国
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Quick Overview for FBLN2 抗体 (AA 501-600) (AbBy Fluor® 488) (ABIN1695415)

抗原

See all FBLN2 抗体
FBLN2 (Fibulin 2 (FBLN2))

适用

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宿主

  • 44
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克隆类型

  • 45
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多克隆

标记

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This FBLN2 antibody is conjugated to AbBy Fluor® 488

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 501-600

    预测反应

    Human,Mouse,Rat,Cow,Sheep

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Fibulin 2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    FBLN2 (Fibulin 2 (FBLN2))

    别名

    Fibulin 2

    背景

    Synonyms: Fibulin-2, Fbln2, FBLN2_HUMAN, FIBL-2, Fibulin-2, OTTHUMP00000216670, OTTHUMP00000216671, OTTHUMP00000216672.

    Background: Fibulin-1 and Fibulin-2 associate with Fibronectin and other extracellular matrix proteins. In bone marrow, Fibulin-1 and Fibulin-2 bind to Fibronectin in the adherent layer. Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and has been suggested as both an agent of metastasis in ovarian cancer cells and as an indicator for predicting cancer risk or aggressiveness in ovarian carcinomas. The mobility of cancer cells may be inhibited with increasing exposure to Fibulin-1. Fibulin-2 binds to the lectin domains of extracellular matrix proteins aggrecan, versican and brevican. Fibulin-2 is abundantly expressed in heart, placenta and ovarian tissue, where it localizes to basement membranes and connective tissue compartments. In mice, differential Fibulin-2 gene expression correlates with the early phase of diabetic kidneys and glomerulosclerosis. The gene encoding human Fibulin-2 maps to chromosome 3p25.1.

    基因ID

    2199
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