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TAZ 抗体 (AA 1-100) (AbBy Fluor® 488)

This anti-TAZ antibody is a 兔 多克隆 antibody detecting TAZ in WB, IF (cc), IF (p) 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1694960
发货至: 中国

Quick Overview for TAZ 抗体 (AA 1-100) (AbBy Fluor® 488) (ABIN1694960)

抗原

See all TAZ 抗体
TAZ (Tafazzin (TAZ))

适用

  • 75
  • 31
  • 31
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 70
  • 8
  • 1
  • 1
  • 1

克隆类型

  • 72
  • 9
多克隆

标记

  • 38
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TAZ antibody is conjugated to AbBy Fluor® 488

应用范围

  • 66
  • 28
  • 25
  • 25
  • 16
  • 15
  • 9
  • 8
  • 8
  • 6
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 15
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human TAZ

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    TAZ (Tafazzin (TAZ))

    别名

    TAZ

    背景

    Synonyms: TAZ, WW domain-containing transcription regulator protein 1, Transcriptional coactivator with PDZ-binding motif, WWTR1

    Background: Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation. Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex. Regulates embryonic stem-cell self-renewal, promotes cell proliferation and epithelial-mesenchymal transition.

    基因ID

    25937

    UniProt

    Q9GZV5
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