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CMKLR1 抗体 (AA 171-280) (AbBy Fluor® 488)

This anti-CMKLR1 antibody is a 兔 多克隆 antibody detecting CMKLR1 in WB, IF (cc) 和 IF (p). Suitable for 人 和 小鼠.
产品编号 ABIN1694684
发货至: 中国

Quick Overview for CMKLR1 抗体 (AA 171-280) (AbBy Fluor® 488) (ABIN1694684)

抗原

See all CMKLR1 抗体
CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This CMKLR1 antibody is conjugated to AbBy Fluor® 488

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 171-280

    交叉反应

    人, 小鼠

    预测反应

    Dog,Sheep

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CMKLR1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))

    别名

    CMKLR1

    背景

    Synonyms: Chemokine receptor-like 1, CHEMR23, ChemR23, DEZ, Chemokine like receptor 1, G protein coupled receptor ChemR23, G protein coupled receptor DEZ, CML1_HUMAN , Orphan G protein coupled receptor.

    Background: Chemokine-Like Receptor 1 (CMKLR1) is a serpentine transmembrane G-protein linked receptor. It is an orphan chemoattractant receptor, also known as ChemR23 or DEZ. CMKLR1 is expressed on the surface of monocyte-derived immature dendritic cells and peripheral plamacytoid dendritic (pDC) cells, but not on myeloid dendritic (mDC) cells, monocytes and lymphocytes. The expression of CMKLR1 on pDC is down-regulated after activation. Chemerin (TIG2) is a natural ligand of CMKLR1. The interaction of CMKLR1 with Chemerin induces pDC activation and chemotaxis. It has been shown that CMKLR1 is a coreceptor for several strains of SIV and HIV-1. CMKLR1 is a potential useful marker for distinguishing pDCs and mDCs.

    基因ID

    1240
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