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FMN1 抗体 (AA 651-750) (AbBy Fluor® 350)

This anti-FMN1 antibody is a 兔 多克隆 antibody detecting FMN1 in WB, IF (cc) 和 IF (p). Suitable for 人 和 大鼠.
产品编号 ABIN1693767
发货至: 中国

Quick Overview for FMN1 抗体 (AA 651-750) (AbBy Fluor® 350) (ABIN1693767)

抗原

See all FMN1 抗体
FMN1 (Formin 1 (FMN1))

适用

  • 27
  • 15
  • 2
人, 大鼠

宿主

  • 24
  • 3

克隆类型

  • 26
  • 1
多克隆

标记

  • 11
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FMN1 antibody is conjugated to AbBy Fluor® 350

应用范围

  • 23
  • 12
  • 12
  • 8
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 651-750

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Dog,Cow,Sheep

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human FMN1/Formin 1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    FMN1 (Formin 1 (FMN1))

    别名

    FMN1/Formin 1

    背景

    Synonyms: FMN, Formin 1, Formin1, Formin-1, LD, Limb deformity protein homolog, FMN1_HUMAN.

    Background: The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. In mice, the limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of proteins known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing Actin filament assembly. Formins co-localize with the actin cytoskeleton and can translocate into the cell cytosol and into the nucleus in an HGF-dependent manner. Vertebrate nuclear formins can control polarizing activity in limb buds through establishment of a Sonic hedgehog/FGF-4 feedback loop. Deficiency mutations at the mammalian ld locus lead to profound developmental defects in limb and kidney formation. The human Formin 1 and 2 genes map to chromosome 15q13.3 and 1q43, respectively.

    基因ID

    342184

    途径

    Regulation of Actin Filament Polymerization
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