CHTOP 抗体 (AA 31-130) (AbBy Fluor® 350)
Quick Overview for CHTOP 抗体 (AA 31-130) (AbBy Fluor® 350) (ABIN1693355)
抗原
See all CHTOP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-130
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human C1orf77
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亚型
- IgG
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anti-Chromatin Target of PRMT1 (CHTOP) (AA 179-248) antibody
CHTOP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Target of PRMT1 (CHTOP) (C-Term) antibodyCHTOP 适用: 人, 小鼠 WB, IHC, IP, IHC (p), ICC 宿主: 大鼠 Monoclonal KT64 unconjugated
anti-Chromatin Target of PRMT1 (CHTOP) (AA 71-120) antibodyCHTOP 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, Pig, 斑马鱼, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CHTOP (Chromatin Target of PRMT1 (CHTOP))
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别名
- C1orf77
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背景
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Synonyms: Chromatin target of PRMT1 protein, Chromosome 1 open reading frame 77, CHTOP, CHTOP_HUMAN, DKFZp547E1010, FOP, Friend of PRMT1 protein, MGC131924, MGC86949, OTTHUMP00000035122, OTTHUMP00000035123, Pp7704, RP1 178F15.2, Small arginine- and glycine-rich protein, Small protein rich in arginine and glycine, SRAG.
Background: C1orf77, also known as Friend of PRMT1 protein, is a 248 amino acid protein that plays an essential role in the ligand-dependent activation of estrogen receptor target genes. C1orf77 is tightly associated with chromatin and is modified by both asymmetric and symmetric arginine methylation. Depletion of C1orf77 results in almost complete block of estradiol-induced promter occupancy by the estrogen receptor. Also, complete knockdown of C1orf77 mRNA in adult erythroid progenitors stongly induces fetal hemoglobin, suggesting that C1orf77 is a critical modulator of _-globin gene expression. There are two isoforms of C1orf77 that are produced as a result of alternative splicing events. The gene encoding C1orf77 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.
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基因ID
- 26097
抗原
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