CRTAP 抗体 (AA 201-300) (AbBy Fluor® 350)
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北京 101111
Quick Overview for CRTAP 抗体 (AA 201-300) (AbBy Fluor® 350) (ABIN1693316)
抗原
See all CRTAP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-300
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交叉反应
- 人
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预测反应
- Mouse,Rat,Dog,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CRTAP
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亚型
- IgG
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anti-Cartilage Associated Protein (CRTAP) (AA 307-401) antibody
CRTAP 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4D9 unconjugated
anti-Cartilage Associated Protein (CRTAP) (AA 26-400) antibodyCRTAP 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Associated Protein (CRTAP) (AA 20-240) antibodyCRTAP 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Associated Protein (CRTAP) antibodyCRTAP 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Associated Protein (CRTAP) antibodyCRTAP 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Associated Protein (CRTAP) (AA 31-59), (N-Term) antibodyCRTAP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Associated Protein (CRTAP) (AA 107-156) antibodyCRTAP 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CRTAP (Cartilage Associated Protein (CRTAP))
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别名
- CRTAP
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背景
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Synonyms: Cartilage associated protein, LEPREL3, leprecan-like 3, CASP, CRTAP_HUMAN.
Background: CRTAP is a secreted protein localizing to the extracellular space that plays a role in collagen post-translational modifications, extracellular fibril assembly and intracellular trafficking. CRTAP is widely expressed with predominant expression in articular chondrocytes. It contains a signal peptide and a tetratricopeptide-like helical domain and is essential for normal bone formation. In the endoplasmic reticulum (ER), CRTAP forms a complex with Gros1 and CyPB (cyclophilin B) and is required for the efficient 3-hydroxylation of target prolyl residues in Collagen Type I molecules, the major structural proteins of skin and bone. Mutations in the gene encoding CRTAP can lead to autosomal recessive osteogenesis imperfecta (OI) type 7 and type 2B. OI, also known as brittle bone disease, is characterized by bone fragility and susceptibility to fractures. OI type 7 is a mild form of this disorder, while OI type 2B is a neonatal lethal condition.
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基因ID
- 10491
抗原
-
