ENPP3 抗体 (APC)
(3 references)Quick Overview for ENPP3 抗体 (APC) (ABIN1690741)
抗原
See all ENPP3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD203c APC
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特异性
- The mouse monoclonal antibody NP4D6 reacts with an extracellular epitope of CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.
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交叉反应 （详细）
- Human
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纯化方法
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- HEK-293 cells transfected with human CD203c
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亚型
- IgG1
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anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (Internal Region) antibody
ENPP3 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (AA 45-163) antibodyENPP3 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 4C1H2 unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (Internal Region) antibodyENPP3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (Internal Region) antibodyENPP3 适用: 人, 犬, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibodyENPP3 适用: 人 FACS, ICC 宿主: 小鼠 Monoclonal NP4D6 unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibody (PE)ENPP3 适用: 人 FACS, ICC 宿主: 小鼠 Monoclonal NP4D6 PE
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (AA 40-140) antibodyENPP3 适用: 人, 大鼠 FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (AA 602-699) antibodyENPP3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibody (FITC)ENPP3 适用: 人 FACS 宿主: 小鼠 Monoclonal NP4D6 FITC
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibodyENPP3 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Extracellular and intracellular staining.
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限制
- 仅限研究用
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溶解方式
- No reconstitution is necessary.
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Do not freeze.
Avoid prolonged exposure to light. -
储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Pimecrolimus Is a Potent Inhibitor of Allergic Reactions to Hymenopteran Venom Extracts and Birch Pollen Allergen In Vitro." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142953, (2015) (PubMed).
: "Hymenoptera-venom-induced upregulation of the basophil activation marker ecto-nucleotide pyrophosphatase/phosphodiesterase 3 in sensitized individuals." in: International archives of allergy and immunology, Vol. 126, Issue 4, pp. 335-42, (2002) (PubMed).
: "The basophil activation marker defined by antibody 97A6 is identical to the ectonucleotide pyrophosphatase/phosphodiesterase 3." in: Blood, Vol. 97, Issue 10, pp. 3303-5, (2001) (PubMed).
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: "Pimecrolimus Is a Potent Inhibitor of Allergic Reactions to Hymenopteran Venom Extracts and Birch Pollen Allergen In Vitro." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142953, (2015) (PubMed).
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- ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))
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别名
- CD203c
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背景
- Ectonucleotide pyrophosphatase/phosphodiesterase 3,CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.,ENPP3, B10, PDNP3, PD-IBETA
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基因ID
- 5169
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UniProt
- O14638
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途径
- Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity
抗原
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