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PDE8A 抗体

This 小鼠 单克隆 anti-PDE8A antibody (Clone EM-52) specifically detects PDE8A in WB. The antibody is reactive with 人 samples.
产品编号 ABIN1690735
发货至: 中国
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Quick Overview for PDE8A 抗体 (ABIN1690735)

抗原

See all PDE8A 抗体
PDE8A (phosphodiesterase 8A (PDE8A))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PDE8A antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

EM-52
  • 原理

    Anti-PDE8A Purified

    特异性

    The mouse monoclonal antibody EM-52 recognizes PDE8a (phosphodiesterase 8 A), an approximately 93 kDa intracellular enzyme that hydrolyzes cAMP to 5'AMP.

    交叉反应 (详细)

    Human

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    Human PDE8a

    亚型

    IgG1 kappa
  • 应用备注

    Western blotting: Recommended dilution: 1-2 μg/mL.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    PDE8A (phosphodiesterase 8A (PDE8A))

    别名

    PDE8A

    背景

    Phosphodiesterase 8A,PDE8a (high affinity cAMP-specific and IBMX-insensitive 3´,5´-cyclic phosphodiesterase 8 A) is a cyclic nucleotide phosphodiesterase, which hydrolyzes cAMP, an important regulator and mediator of multiple cellular responses to extracellular signals. It is expressed in a wide variety of tissues including testis, ovary, small intestine, and colon. It is not expressed e.g. in thymus. PDE8a is composed of C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.,HsT19550

    基因ID

    5151

    UniProt

    O60658

    途径

    cAMP Metabolic Process
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