PDE8A 抗体
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北京 101111
Quick Overview for PDE8A 抗体 (ABIN1690735)
抗原
See all PDE8A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-PDE8A Purified
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特异性
- The mouse monoclonal antibody EM-52 recognizes PDE8a (phosphodiesterase 8 A), an approximately 93 kDa intracellular enzyme that hydrolyzes cAMP to 5'AMP.
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交叉反应 (详细)
- Human
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Human PDE8a
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亚型
- IgG1 kappa
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应用备注
- Western blotting: Recommended dilution: 1-2 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- PDE8A (phosphodiesterase 8A (PDE8A))
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别名
- PDE8A
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背景
- Phosphodiesterase 8A,PDE8a (high affinity cAMP-specific and IBMX-insensitive 3´,5´-cyclic phosphodiesterase 8 A) is a cyclic nucleotide phosphodiesterase, which hydrolyzes cAMP, an important regulator and mediator of multiple cellular responses to extracellular signals. It is expressed in a wide variety of tissues including testis, ovary, small intestine, and colon. It is not expressed e.g. in thymus. PDE8a is composed of C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.,HsT19550
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基因ID
- 5151
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UniProt
- O60658
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途径
- cAMP Metabolic Process
抗原
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