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PR 抗体

This 小鼠 单克隆 antibody specifically detects PR in WB, ELISA 和 IHC. It exhibits reactivity toward 人. It has been mentioned in 5+ publications
产品编号 ABIN1689598
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PR 抗体 (ABIN1689598)

抗原

PR

适用

  • 8
  • 3
  • 2
  • 1
  • 1

宿主

  • 6
  • 2
小鼠

克隆类型

  • 6
  • 2
单克隆

标记

  • 8
非结合性

应用范围

  • 7
  • 6
  • 5
  • 5
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

2F12B4-2F12H2
  • 纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of PR expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Jowett: "Safe Motherhood interventions in low-income countries: an economic justification and evidence of cost effectiveness." in: Health policy (Amsterdam, Netherlands), Vol. 53, Issue 3, pp. 201-28, (2000) (PubMed).

    Hagen, Silva, Amorim, Hagedoorn, Wassink, Haaker, Robb: "Novel structure and redox chemistry of the prosthetic groups of the iron-sulfur flavoprotein sulfide dehydrogenase from Pyrococcus furiosus; evidence for a [2Fe-2S] cluster with Asp(Cys)3 ligands." in: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, Vol. 5, Issue 4, pp. 527-34, (2000) (PubMed).

    Wen, Xu, Mais, Goldman, McDonnell: "The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells." in: Molecular and cellular biology, Vol. 14, Issue 12, pp. 8356-64, (1994) (PubMed).

    McGuire: "Prognostic factors in primary breast cancer." in: Cancer surveys, Vol. 5, Issue 3, pp. 527-36, (1987) (PubMed).

    Bach: "Markets in kidneys." in: Lancet, Vol. 2, Issue 8411, pp. 1102, (1984) (PubMed).

  • 抗原

    PR

    背景

    PR(progesterone receptor), with 933-amino acid protein (about 110kDa), a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone, PR is mediated by two functionally different isoforms of the progesterone receptor, the full length PR-B and the short form PR-A. The PR-A and PR-B proteins are 94 kDa and 114 kDa respectively. That are equimolar in the normal breast but dysregulated in advanced disease. PR is prognostic markers in breast cancers irrespective of the patient's progestational status Human progesterone.
    Synonyms: PR, NR3C3, PGR

    基因ID

    5241
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