SYT7 抗体 (AA 150-239)
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Quick Overview for SYT7 抗体 (AA 150-239) (ABIN1686633)
抗原
See all SYT7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 150-239
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特异性
- Detects ~45 kDa. Does not cross-react with Synaptotagmin-6 (or others). Can identify other isoforms bands at ~65kD.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Protein G Purified
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免疫原
- Fusion protein amino acids 150-239 (Cytoplasmic C2A domain) of mouse Synaptotagmin-7
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亚型
- IgG2b
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anti-Synaptotagmin VII (SYT7) antibody
SYT7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin VII (SYT7) (AA 150-239) antibody (HRP)SYT7 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S275-14 HRP
anti-Synaptotagmin VII (SYT7) (AA 150-239) antibody (FITC)SYT7 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S275-14 FITC
anti-Synaptotagmin VII (SYT7) (AA 150-239) antibody (Biotin)SYT7 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S275-14 Biotin
anti-Synaptotagmin VII (SYT7) (AA 150-239) antibody (PE)SYT7 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S275-14 PE
anti-Synaptotagmin VII (SYT7) (AA 150-239) antibody (PerCP)SYT7 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S275-14 PerCP
anti-Synaptotagmin VII (SYT7) (AA 150-239) antibody (APC)SYT7 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S275-14 APC
anti-Synaptotagmin VII (SYT7) (AA 150-239) antibody (Atto 594)SYT7 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S275-14 Atto 594
anti-Synaptotagmin VII (SYT7) (AA 150-239) antibody (Atto 488)SYT7 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S275-14 Atto 488
anti-Synaptotagmin VII (SYT7) (AA 150-239) antibody (Atto 390)SYT7 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S275-14 Atto 390
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应用备注
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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说明
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1 μg/ml of ABIN1686633 was sufficient for detection of Synaptotagmin-7 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C
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- SYT7 (Synaptotagmin VII (SYT7))
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别名
- Synaptotagmin 7
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背景
- Synaptotagmins constitute a family of membrane-trafficking proteins that are characterized by an N-terminal transmembrane region (TMR), a variable linker, and two C-terminal C2 domains - C2A and C2B. There are 15 members in the mammalian synaptotagmin family. There are several C2-domain containing protein families that are related to synaptotagmins, including transmembrane (Ferlins, E-Syts, and MCTPs) and soluble (RIMs, Munc13s, synaptotagmin-related proteins and B/K) proteins. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first domain mediates Ca(2+)-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2. Synaptotagmin may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacylbackbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner, these are neurexins, syntaxin and AP2.
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基因ID
- 54525
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NCBI登录号
- NP_061271
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UniProt
- Q9R0N7
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途径
- Synaptic Vesicle Exocytosis
抗原
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