GTPBP4 抗体
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北京 101111
Quick Overview for GTPBP4 抗体 (ABIN1683278)
抗原
See all GTPBP4 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human GTPBP4
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GTPBP4 (GTP Binding Protein 4 (GTPBP4))
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别名
- GTPBP4
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背景
- GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008],CRFG, NGB, NOG1,Cancer,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Tumor suppressors,GTPBP4
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分子量
- 80 kDa
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基因ID
- 23560
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UniProt
- Q9BZE4
抗原
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