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TPSAB1 抗体 (AA 19-210)

This anti-TPSAB1 antibody is a 兔 多克隆 antibody detecting TPSAB1 in WB. Suitable for 人.
产品编号 ABIN1683115
发货至: 中国

Quick Overview for TPSAB1 抗体 (AA 19-210) (ABIN1683115)

抗原

See all TPSAB1 抗体
TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TPSAB1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 19-210

    序列

    APAPGQALQR VGIVGGQEAP RSKWPWQVSL RVHGPYWMHF CGGSLIHPQW VLTAAHCVGP DVKDLAALRV QLREQHLYYQ DQLLPVSRII VHPQFYTAQI GADIALLELE EPVNVSSHVH TVTLPPASET FPPGMPCWVT GWGDVDNDER LPPPFPLKQV KVPIMENHIC DAKYHLGAYT GDDVRIVRDD ML

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 19-210 of human TPSAB1 (NP_003285.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

    别名

    TPSAB1

    背景

    Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.,TPSAB1,TPS1,TPS2,TPSB1,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,TPSAB1

    分子量

    29 kDa/30 kDa

    基因ID

    7177

    UniProt

    Q15661
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