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TGFB2 抗体 (AA 20-160)

This anti-TGFB2 antibody (ABIN1683015) is a Rabbit Polyclonal antibody detecting TGFB2 in WB. Suitable for Human.
产品编号 ABIN1683015
发货至: 中国

Quick Overview for TGFB2 抗体 (AA 20-160) (ABIN1683015)

抗原

See all TGFB2 抗体
TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

适用

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宿主

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克隆类型

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多克隆

标记

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This TGFB2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 20-160

    序列

    SLSTCSTLDM DQFMRKRIEA IRGQILSKLK LTSPPEDYPE PEEVPPEVIS IYNSTRDLLQ EKASRRAAAC ERERSDEEYY AKEVYKIDMP PFFPSETVCP VVTTPSGSVG SLCSRQSQVL CGYLDAIPPT FYRPYFRIVR F

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 20-160 of human TGFB2 (NP_001129071.1).

    亚型

    IgG
  • 应用备注

    WB,1:200 - 1:2000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

    别名

    TGFB2

    背景

    This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1,7)(q41,p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.,TGFB2,G-TSF,LDS4,TGF-beta2,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Growth factor,TGF-b-Smad Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Endocrine & Metabolism,Stem Cells,Cardiovascular,Angiogenesis,Angiogenic growth factors,Ligand,TGFB2

    分子量

    47 kDa/50 kDa

    基因ID

    7042

    UniProt

    P61812

    途径

    Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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