PEG10 抗体 (AA 1-325)
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北京 101111
Quick Overview for PEG10 抗体 (AA 1-325) (ABIN1681320)
抗原
See all PEG10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-325
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序列
- MTERRRDELS EEINNLREKV MKQSEENNNL QSQVQKLTEE NTTLREQVEP TPEDEDDDIE LRGAAAAAAP PPPIEEECPE DLPEKFDGNP DMLAPFMAQC QIFMEKSTRD FSVDRVRVCF VTSMMTGRAA RWASAKLERS HYLMHNYPAF MMEMKHVFED PQRREVAKRK IRRLRQGMGS VIDYSNAFQM IAQDLDWNEP ALIDQYHEGL SDHIQEELSH LEVAKSLSAL IGQCIHIERR LARAAAARKP RSPPRALVLP HIASHHQVDP TEPVGGARMR LTQEEKERRR KLNLCLYCGT GGHYADNCPA KASKSSPAGN SPAPL
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human PEG10 (NP_001035242.1).
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亚型
- IgG
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anti-Paternally Expressed 10 (PEG10) (AA 1-120) antibody
PEG10 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 1B1C4 unconjugated
anti-Paternally Expressed 10 (PEG10) (AA 1-325) antibodyPEG10 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Paternally Expressed 10 (PEG10) (AA 1-325) antibodyPEG10 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paternally Expressed 10 (PEG10) antibodyPEG10 适用: 人 WB, IP 宿主: 小鼠 Monoclonal unconjugated
anti-Paternally Expressed 10 (PEG10) (AA 1-30), (N-Term) antibodyPEG10 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB31292 unconjugated
anti-Paternally Expressed 10 (PEG10) (AA 1-30), (N-Term) antibodyPEG10 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:200 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PEG10 (Paternally Expressed 10 (PEG10))
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别名
- PEG10
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背景
- This is a paternally expressed imprinted gene that is thought to have been derived from the Ty3/Gypsy family of retrotransposons. It contains two overlapping open reading frames, RF1 and RF2, and expresses two proteins: a shorter, gag-like protein (with a CCHC-type zinc finger domain) from RF1, and a longer, gag/pol-like fusion protein (with an additional aspartic protease motif) from RF1/RF2 by -1 translational frameshifting (-1 FS). While -1 FS has been observed in RNA viruses and transposons in both prokaryotes and eukaryotes, this gene represents the first example of -1 FS in a eukaryotic cellular gene. This gene is highly conserved across mammalian species and retains the heptanucleotide (GGGAAAC) and pseudoknot elements required for -1 FS. It is expressed in adult and embryonic tissues (most notably in placenta) and reported to have a role in cell proliferation, differentiation and apoptosis. Overexpression of this gene has been associated with several malignancies, such as hepatocellular carcinoma and B-cell lymphocytic leukemia. Knockout mice lacking this gene showed early embryonic lethality with placental defects, indicating the importance of this gene in embryonic development. Additional isoforms resulting from alternatively spliced transcript variants, and use of upstream non-AUG (CUG) start codon have been reported for this gene.,PEG10,EDR,HB-1,MEF3L,Mar2,Mart2,RGAG3,RTL2,SIRH1,Epigenetics & Nuclear Signaling,Transcription Factors,RNA Binding,Cancer,Stem Cells,Germline Stem Cells,PEG10
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分子量
- 36 kDa/80 kDa
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基因ID
- 23089
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UniProt
- Q86TG7
抗原
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