NPLOC4 抗体 (AA 1-270)
Quick Overview for NPLOC4 抗体 (AA 1-270) (ABIN1681086)
抗原
See all NPLOC4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-270
-
序列
- MAESIIIRVQ SPDGVKRITA TKRETAATFL KKVAKEFGFQ NNGFSVYINR NKTGEITASS NKSLNLLKIK HGDLLFLFPS SLAGPSSEME TSVPPGFKVF GAPNVVEDEI DQYLSKQDGK IYRSRDPQLC RHGPLGKCVH CVPLEPFDED YLNHLEPPVK HMSFHAYIRK LTGGADKGKF VALENISCKI KSGCEGHLPW PNGICTKCQP SAITLNRQKY RHVDNIMFEN HTVADRFLDF WRKTGNQHFG YLYGRYTEHK DIPLGIRAEV
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human NPLOC4 (NP_060391.2).
-
亚型
- IgG
-
-
anti-Nuclear Protein Localization 4 Homolog (NPLOC4) (AA 1-608) antibody
NPLOC4 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Protein Localization 4 Homolog (NPLOC4) (AA 1-608) antibodyNPLOC4 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Protein Localization 4 Homolog (NPLOC4) (AA 96-145) antibodyNPLOC4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB,1:1000 - 1:2000,IF,1:50 - 1:200
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))
-
别名
- NPLOC4
-
背景
- The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity. Acts as a negative regulator of type I interferon production via the complex formed with VCP and UFD1, which binds to DDX58/RIG-I and recruits RNF125 to promote ubiquitination and degradation of DDX58/RIG-I.,NPLOC4,NPL4,NPL4 homolog,Signal Transduction,NPLOC4
-
分子量
- 68 kDa/69 kDa
-
基因ID
- 55666
-
UniProt
- Q8TAT6
抗原
-
