MYCN 抗体 (AA 168-267)
Quick Overview for MYCN 抗体 (AA 168-267) (ABIN1680957)
抗原
See all MYCN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 168-267
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序列
- AGRAGAALPA ELAHPAAECV DPAVVFPFPV NKREPAPVPA APASAPAAGP AVASGAGIAA PAGAPGVAPP RPGGRQTSGG DHKALSTSGE DTLSDSDDED
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 168-267 of human MYCN (NP_005369.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer." in: American journal of translational research, Vol. 8, Issue 2, pp. 1133-43, (2016) (PubMed).
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: "Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer." in: American journal of translational research, Vol. 8, Issue 2, pp. 1133-43, (2016) (PubMed).
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- MYCN (N-Myc Proto-Oncogene Protein (MYCN))
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别名
- MYCN
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背景
- This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.,MODED,N-myc,NMYC,ODED,bHLHe37,MYCN,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,MAPK-Erk Signaling Pathway,MYCN
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分子量
- 49 kDa
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基因ID
- 4613
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UniProt
- P04198
抗原
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