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MYCN 抗体 (AA 168-267)

Cited in 1 publication. This 兔 多克隆 anti-MYCN antibody specifically detects MYCN in WB, IHC 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN1680957
发货至: 中国
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Quick Overview for MYCN 抗体 (AA 168-267) (ABIN1680957)

抗原

See all MYCN 抗体
MYCN (N-Myc Proto-Oncogene Protein (MYCN))

适用

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宿主

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克隆类型

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多克隆

标记

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This MYCN antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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    AA 168-267

    序列

    AGRAGAALPA ELAHPAAECV DPAVVFPFPV NKREPAPVPA APASAPAAGP AVASGAGIAA PAGAPGVAPP RPGGRQTSGG DHKALSTSGE DTLSDSDDED

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 168-267 of human MYCN (NP_005369.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Chang, Yang, Zheng, Li, Nie: "Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer." in: American journal of translational research, Vol. 8, Issue 2, pp. 1133-43, (2016) (PubMed).

  • 抗原

    MYCN (N-Myc Proto-Oncogene Protein (MYCN))

    别名

    MYCN

    背景

    This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.,MODED,N-myc,NMYC,ODED,bHLHe37,MYCN,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,MAPK-Erk Signaling Pathway,MYCN

    分子量

    49 kDa

    基因ID

    4613

    UniProt

    P04198
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