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RAP1GAP 抗体

This 兔 单克隆 anti-RAP1GAP antibody specifically detects RAP1GAP in WB 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN1680949
发货至: 中国
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Quick Overview for RAP1GAP 抗体 (ABIN1680949)

抗原

See all RAP1GAP 抗体
RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

适用

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宿主

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克隆类型

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单克隆

标记

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This RAP1GAP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human Rap1GAP

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

    别名

    RAP1GAP

    背景

    This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Aug 2011],RAP1GA1, RAP1GAP1, RAP1GAPII, RAPGAP,Cancer,Epigenetics & Nuclear Signaling,Signal Transduction,Tumor suppressors,RAP1GAP

    分子量

    95 kDa

    基因ID

    5909

    UniProt

    P47736
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