IRF4 抗体 (AA 150-350)
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北京 101111
Quick Overview for IRF4 抗体 (AA 150-350) (ABIN1680506)
抗原
See all IRF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-350
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序列
- HPYTMTTPYP SLPAQQVHNY MMPPLDRSWR DYVPDQPHPE IPYQCPMTFG PRGHHWQGPA CENGCQVTGT FYACAPPESQ APGVPTEPSI RSAEALAFSD CRLHICLYYR EILVKELTTS SPEGCRISHG HTYDASNLDQ VLFPYPEDNG QRKNIEKLLS HLERGVVLWM APDGLYAKRL CQSRIYWDGP LALCNDRPNK L
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 150-350 of human IRF4 (NP_002451.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- IRF4 (Interferon Regulatory Factor 4 (IRF4))
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别名
- IRF4
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背景
- The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.,IRF4,LSIRF,MUM1,NF-EM5,SHEP8,IRF-4,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,IRF4
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分子量
- 51 kDa
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基因ID
- 3662
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UniProt
- Q15306
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途径
- Chromatin Binding
抗原
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