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Integrin beta 4 抗体 (AA 28-310)

This anti-Integrin beta 4 antibody is a 兔 多克隆 antibody detecting Integrin beta 4 in WB 和 IHC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1680489
发货至: 中国

Quick Overview for Integrin beta 4 抗体 (AA 28-310) (ABIN1680489)

抗原

See all Integrin beta 4 (ITGB4) 抗体
Integrin beta 4 (ITGB4)

适用

  • 91
  • 27
  • 24
  • 4
  • 4

宿主

  • 64
  • 38
  • 10
  • 2

克隆类型

  • 57
  • 57
多克隆

标记

  • 64
  • 9
  • 7
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Integrin beta 4 antibody is un-conjugated

应用范围

  • 58
  • 50
  • 42
  • 34
  • 23
  • 22
  • 16
  • 13
  • 13
  • 13
  • 9
  • 8
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 10
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-310

    序列

    NRCKKAPVKS CTECVRVDKD CAYCTDEMFR DRRCNTQAEL LAAGCQRESI VVMESSFQIT EETQIDTTLR RSQMSPQGLR VRLRPGEERH FELEVFEPLE SPVDLYILMD FSNSMSDDLD NLKKMGQNLA RVLSQLTSDY TIGFGKFVDK VSVPQTDMRP EKLKEPWPNS DPPFSFKNVI SLTEDVDEFR NKLQGERISG NLDAPEGGFD AILQTAVCTR DIGWRPDSTH LLVFSTESAF HYEADGANVL AGIMSRNDER CHLDTTGTYT QYRTQDYPSV PTL

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 28-310 of human Integrin beta 4 (ITGB4/CD104) (NP_000204.3).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:100

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Feng, Chen, Ding, Fu, Yang, Deng, Zeng: "P2X7R blockade prevents NLRP3 inflammasome activation and brain injury in a rat model of intracerebral hemorrhage: involvement of peroxynitrite." in: Journal of neuroinflammation, Vol. 12, pp. 190, (2016) (PubMed).

  • 抗原

    Integrin beta 4 (ITGB4)

    别名

    ITGB4

    背景

    Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,ITGB4,CD104,GP150,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,ITGB4

    分子量

    106 kDa/194 kDa/195 kDa/200 kDa/202 kDa

    基因ID

    3691

    UniProt

    P16144

    途径

    Integrin Complex
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