GNB3 抗体 (AA 1-230)
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北京 101111
Quick Overview for GNB3 抗体 (AA 1-230) (ABIN1680055)
抗原
See all GNB3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-230
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序列
- MGEMEQLRQE AEQLKKQIAD ARKACADVTL AELVSGLEVV GRVQMRTRRT LRGHLAKIYA MHWATDSKLL VSASQDGKLI VWDSYTTNKV HAIPLRSSWV MTCAYAPSGN FVACGGLDNM CSIYNLKSRE GNVKVSRELS AHTGYLSCCR FLDDNNIVTS SGDTTCALWD IETGQQKTVF VGHTGDCMSL AVSPDFNLFI SGACDASAKL WDVREGTCRQ TFTGHESDIN
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human GNB3 (NP_002066.1).
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亚型
- IgG
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anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3) (AA 101-200) antibody
GNB3 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3) (AA 1-340) antibodyGNB3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal M1-1-1D5 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3) antibodyGNB3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4330 unconjugated Recombinant Antibody
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3) (Internal Region) antibodyVerified GNB3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3) (Internal Region) antibody (Biotin)Verified GNB3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal Biotin
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3) (C-Term) antibodyGNB3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))
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别名
- GNB3
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背景
- Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.,GNB3,CSNB1H,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Phospholipase Signaling Pathway,MAPK-JNK Signaling Pathway,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Cardiovascular,Blood,Blood Pressure regulation,GNB3
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分子量
- 32 kDa/37 kDa
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基因ID
- 2784
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UniProt
- P16520
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途径
- Peptide Hormone Metabolism, Myometrial Relaxation and Contraction
抗原
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