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GNB3 抗体 (AA 1-230)

GNB3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1680055
发货至: 中国
  • 抗原 See all GNB3 抗体
    GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))
    抗原表位
    • 15
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 1-230
    适用
    • 24
    • 19
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 35
    • 2
    • 2
    • 1
    克隆类型
    • 39
    • 1
    多克隆
    标记
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This GNB3 antibody is un-conjugated
    应用范围
    • 26
    • 26
    • 24
    • 12
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    MGEMEQLRQE AEQLKKQIAD ARKACADVTL AELVSGLEVV GRVQMRTRRT LRGHLAKIYA MHWATDSKLL VSASQDGKLI VWDSYTTNKV HAIPLRSSWV MTCAYAPSGN FVACGGLDNM CSIYNLKSRE GNVKVSRELS AHTGYLSCCR FLDDNNIVTS SGDTTCALWD IETGQQKTVF VGHTGDCMSL AVSPDFNLFI SGACDASAKL WDVREGTCRQ TFTGHESDIN
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human GNB3 (NP_002066.1).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))
    别名
    GNB3 (GNB3 产品)
    别名
    Gnb-3 antibody, MGC68913 antibody, MGC130764 antibody, gnb3 antibody, zgc:73058 antibody, zgc:77780 antibody, wu:fk54b04 antibody, gnb3l antibody, zgc:92641 antibody, G protein subunit beta 3 antibody, guanine nucleotide binding protein (G protein), beta 3 antibody, guanine nucleotide binding protein (G protein), beta polypeptide 3 S homeolog antibody, guanine nucleotide binding protein (G protein), beta polypeptide 3b antibody, guanine nucleotide binding protein (G protein), beta polypeptide 3a antibody, GNB3 antibody, Gnb3 antibody, gnb3.S antibody, gnb3b antibody, gnb3a antibody
    背景
    Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.,GNB3,CSNB1H,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Phospholipase Signaling Pathway,MAPK-JNK Signaling Pathway,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Cardiovascular,Blood,Blood Pressure regulation,GNB3
    分子量
    32 kDa/37 kDa
    基因ID
    2784
    UniProt
    P16520
    途径
    Peptide Hormone Metabolism, Myometrial Relaxation and Contraction
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