TNNI2 抗体
Our Local Distributor
北京 101111
Quick Overview for TNNI2 抗体 (ABIN1679777)
抗原
See all TNNI2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 小鼠, 大鼠
-
产品特性
- Monoclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- A synthesized peptide derived from human Troponin I2 (Troponin I2 (TNNI2))
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- TNNI2 (Fast Skeletal Troponin I (TNNI2))
-
别名
- TNNI2
-
背景
- This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009],AMCD2B, DA2B, FSSV, fsTnI,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Signal Transduction,TNNI2
-
分子量
- 21 kDa
-
基因ID
- 7136
-
UniProt
- P48788
抗原
-