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EPOR 抗体 (AA 274-508)

This anti-EPOR antibody is a 兔 多克隆 antibody detecting EPOR in WB 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1679741
发货至: 中国

Quick Overview for EPOR 抗体 (AA 274-508) (ABIN1679741)

抗原

EPOR (Erythropoietin Receptor (EPOR))

适用

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  • 1
  • 1

宿主

  • 106
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  • 4
  • 1

克隆类型

  • 112
  • 25
  • 1
多克隆

标记

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This EPOR antibody is un-conjugated

应用范围

  • 107
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  • 5
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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    • 1
    AA 274-508

    序列

    HRRALKQKIW PGIPSPESEF EGLFTTHKGN FQLWLYQNDG CLWWSPCTPF TEDPPASLEV LSERCWGTMQ AVEPGTDDEG PLLEPVGSEH AQDTYLVLDK WLLPRNPPSE DLPGPGGSVD IVAMDEGSEA SSCSSALASK PSPEGASAAS FEYTILDPSS QLLRPWTLCP ELPPTPPHLK YLYLVVSDSG ISTDYSSGDS QGAQGGLSDG PYSNPYENSL IPAAEPLPPS YVACS

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 274-508 of human EPOR (NP_000112.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Kai-lan, Si: "Pretreatment With Erythropoietin Attenuates Intestinal Ischemia Reperfusion Injury by Further Promoting PI3K/Akt Signaling Activation." in: Transplantation proceedings, Vol. 47, Issue 6, pp. 1639-45, (2016) (PubMed).

  • 抗原

    EPOR (Erythropoietin Receptor (EPOR))

    别名

    EPOR

    背景

    This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.,EPOR,EPO-R,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,Stem Cells,Hematopoietic Progenitors,Cardiovascular,Angiogenesis,Heart,Hypertrophy,EPOR

    分子量

    26 kDa/35 kDa/55 kDa

    基因ID

    2057

    UniProt

    P19235

    途径

    JAK/STAT Signaling
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