CDH1,CDH2,CDH3,CDH4 抗体
This 兔 单克隆 antibody specifically detects CDH1,CDH2,CDH3,CDH4 in WB 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN1679719
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for CDH1,CDH2,CDH3,CDH4 抗体 (ABIN1679719)
抗原
CDH1,CDH2,CDH3,CDH4
适用
人
宿主
兔
克隆类型
单克隆
标记
非结合性
应用范围
Western Blotting (WB), Immunohistochemistry (IHC)
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human Pan Cadherin
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亚型
- IgG
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anti-CDH1,CDH2,CDH3,CDH4 (AA 800-882) antibody
适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CDH1,CDH2,CDH3,CDH4
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别名
- CDH1/CDH2/CDH3/CDH4
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背景
- This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015],Arc-1, CD324, CDHE, ECAD, LCAM, UVO,Apoptosis,Calcium Signaling,Cancer,CDs,Cell Adhesion,Cell Adhesion_Cadherins,Cell Adhesion_Tight Junctions,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Centrosome,Cytoskeleton,ErbB-HER Signaling Pathway,Immunology & Inflammation,Invasion and Metastasis,Neuroscience,Signal Transduction,Wnt/β-Catenin Signaling Pathway,CDH1/CDH2/CDH3/CDH4
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分子量
- 140 kDa
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基因ID
- 999, 1000, 1001
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UniProt
- P12830, P19022, P22223, P33151, P55283, P39038
抗原
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