DRG1 抗体 (AA 158-367)
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北京 101111
Quick Overview for DRG1 抗体 (AA 158-367) (ABIN1679602)
抗原
See all DRG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 158-367
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序列
- KKIIENELEG FGIRLNSKPP NIGFKKKDKG GINLTATCPQ SELDAETVKS ILAEYKIHNA DVTLRSDATA DDLIDVVEGN RVYIPCIYVL NKIDQISIEE LDIIYKVPHC VPISAHHRWN FDDLLEKIWD YLKLVRIYTK PKGQLPDYTS PVVLPYSRTT VEDFCMKIHK NLIKEFKYAL VWGLSVKHNP QKVGKDHTLE DEDVIQIVKK
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 158-367 of human DRG1 (NP_004138.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- DRG1 (Developmentally Regulated GTP Binding Protein 1 (DRG1))
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别名
- DRG1
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背景
- Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions. When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation. Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these microtubule-related functions.,DRG1,NEDD3,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,DRG1
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分子量
- 40 kDa
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基因ID
- 4733
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UniProt
- Q9Y295
抗原
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