CKMT1A 抗体 (AA 258-417)
Quick Overview for CKMT1A 抗体 (AA 258-417) (ABIN1679244)
抗原
See all CKMT1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 258-417
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序列
- FLIWVNEEDH TRVISMEKGG NMKRVFERFC RGLKEVERLI QERGWEFMWN ERLGYILTCP SNLGTGLRAG VHIKLPLLSK DSRFPKILEN LRLQKRGTGG VDTAATGGVF DISNLDRLGK SEVELVQLVI DGVNYLIDCE RRLERGQDIR IPTPVIHTKH
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 258-417 of human CKMT1A (NP_001015001.1).
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亚型
- IgG
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anti-Creatine Kinase, Mitochondrial 1A (CKMT1A) (AA 41-250) antibody
CKMT1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Mitochondrial 1A (CKMT1A) (AA 40-417) antibodyCKMT1A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Mitochondrial 1A (CKMT1A) (pTyr153) antibodyCKMT1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
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别名
- CKMT1A
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背景
- Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.,CKMT1A,CKMT1,U-MtCK,mia-CK,Signal Transduction,Kinase,CKMT1A
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分子量
- 47 kDa/50 kDa
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基因ID
- 548596
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UniProt
- P12532
抗原
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