BIN1 抗体 (AA 230-409)
Quick Overview for BIN1 抗体 (AA 230-409) (ABIN1678863)
抗原
See all BIN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 230-409
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序列
- QNLNDVLVGL EKQHGSNTFT VKAQPSDNAP AKGNKSPSPP DGSPAATPEI RVNHEPEPAG GATPGATLPK SPSQSSLPAV VVETFPATVN GTVEGGSGAG RLDLPPGFMF KVQAQHDYTA TDTDELQLKA GDVVLVIPFQ NPEEQDEGWL MGVKESDWNQ HKELEKCRGV FPENFTERVP
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交叉反应
- 人, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 230-409 of human BIN1 (NP_647601.1).
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亚型
- IgG
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anti-Bridging Integrator 1 (BIN1) (AA 189-398) antibody
BIN1 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3B6F10 unconjugated
anti-Bridging Integrator 1 (BIN1) antibodyBIN1 适用: 人, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 1 (BIN1) antibodyBIN1 适用: 人 WB, IHC, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 1 (BIN1) (AA 189-398) antibodyBIN1 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3B6A4 unconjugated
anti-Bridging Integrator 1 (BIN1) (AA 414-593) antibodyBIN1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 1 (BIN1) (AA 1-482) antibodyBIN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 1 (BIN1) (AA 355-454) antibodyBIN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-Bridging Integrator 1 (BIN1) antibodyBIN1 适用: 小鼠 WB, IHC, ELISA, IP 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Bridging Integrator 1 (BIN1) antibodyBIN1 适用: 人, 小鼠 WB, IHC, ELISA, IP, FACS 宿主: 小鼠 Monoclonal 99D unconjugated
anti-Bridging Integrator 1 (BIN1) (AA 360-389) antibodyBIN1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:20 - 1:50
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- BIN1 (Bridging Integrator 1 (BIN1))
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别名
- BIN1
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背景
- This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.,BIN1,AMPH2,AMPHL,SH3P9,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,BIN1
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分子量
- 45-64 kDa
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基因ID
- 274
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UniProt
- O00499
抗原
-
