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Bestrophin 1 抗体 (AA 200-300)

This anti-Bestrophin 1 antibody is a 兔 多克隆 antibody detecting Bestrophin 1 in WB. Suitable for 人.
产品编号 ABIN1678855
发货至: 中国

Quick Overview for Bestrophin 1 抗体 (AA 200-300) (ABIN1678855)

抗原

See all Bestrophin 1 (BEST1) 抗体
Bestrophin 1 (BEST1)

适用

  • 23
  • 4
  • 3
  • 2
  • 2
  • 1

宿主

  • 21
  • 4

克隆类型

  • 23
  • 2
多克隆

标记

  • 16
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Bestrophin 1 antibody is un-conjugated

应用范围

  • 17
  • 8
  • 7
  • 5
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-300

    序列

    RIRDPILLQS LLNEMNTLRT QCGHLYAYDW ISIPLVYTQV VTVAVYSFFL TCLVGRQFLN PAKAYPGHEL DLVVPVFTFL QFFFYVGWLK VAEQLINPFG E

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 200-300 of human BEST1 (NP_004174.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Bestrophin 1 (BEST1)

    别名

    BEST1

    背景

    This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.,BEST1,ARB,BEST,BMD,RP50,TU15B,VMD2,Cell Biology & Developmental Biology,Cell Adhesion,Neuroscience,BEST1

    分子量

    57 kDa/67 kDa/69 kDa

    基因ID

    7439

    UniProt

    O76090
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