NCR1 抗体 (AA 22-255)
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Quick Overview for NCR1 抗体 (AA 22-255) (ABIN165440)
抗原
See all NCR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 22-255
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原理
- Human NKp46/NCR1 antibody
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纯化方法
- Purified
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免疫原
- Recombinant human Nkp46 (22-255aa) purified from E. coli
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亚型
- IgG1 kappa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
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别名
- NKp46/NCR1
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背景
- A natural cytotoxicity receptor (NCR), Nkp46, is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 residue stalk resion, a type I transmembrane domain, and a short cytoplasmic tail. Nkp46 has been shown to represent a novel Nk cell-specific molecule involved in human Nk cell activation. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. Nkp46 has been implicated in Nk cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.
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NCBI登录号
- NP_004820
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途径
- Regulation of Leukocyte Mediated Immunity
抗原
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