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SNCA 抗体 (AA 61-95)

This anti-SNCA antibody is a 小鼠 单克隆 antibody detecting SNCA in WB, ELISA, IF 和 ICC. Suitable for 人.
产品编号 ABIN165434
发货至: 中国

Quick Overview for SNCA 抗体 (AA 61-95) (ABIN165434)

抗原

See all SNCA 抗体
SNCA (Synuclein, alpha (SNCA))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SNCA antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

5C2
  • 抗原表位

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    AA 61-95

    纯化方法

    The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

    免疫原

    Recombinant human alpha-synuclein (61-95) purified from E. coli

    亚型

    IgG1 kappa
  • 应用备注

    The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1:2,000. This antibody (5C2) has the specificity against the NAC domain (61-95aa) of alpha-synuclein. Recommended starting dilution is 1:1,000.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    SNCA (Synuclein, alpha (SNCA))

    别名

    alpha-Synuclein

    背景

    Alpha-synuclein (amino acids 1-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Specially, the non-Abeta component of amyloid plaques (NAC, amino acids 61-95) is a highly amyloidogenic peptide consisting of 35 amino acids which was first identified associated with senile plaques in the Alzheimer's disease brain.

    NCBI登录号

    NP_000336

    途径

    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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