Geminin 抗体 (AA 1-209)
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Quick Overview for Geminin 抗体 (AA 1-209) (ABIN165400)
抗原
See all Geminin (GMNN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-209
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原理
- Human Geminin antibody
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纯化方法
- Purified
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免疫原
- Recombinant human Geminin (1-209 aa) purified from E. coli
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亚型
- IgG1 kappa
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应用备注
- Recommended dilution 1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
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别名
- Geminin
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背景
- Geminin is a 25 kDa protein, which inhibits DNA replication and is degraded during the mitotic phase of the cell cycle. Geminin controls replication by binding to the licensing factor Cdt1, and is involved in neural differentiation. In addition, geminin directly interacts with Six3 and Hox homeodomain proteins during embryogenesis and inhibits their functions.
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NCBI登录号
- NP_056979
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途径
- EGFR Signaling Pathway, DNA Replication
抗原
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